Tribac 250 mg/vial (IM Injection)
250 mg vial: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity
- Interferes with the synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Long plasma elimination half-life of 6 to 9 hours
- Not metabolized in the body
- Excreted unchanged in urine and bile
- Highly protein bound (95%)
Dosage
- Adult dosage: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Infants and Children dosage: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Should be dissolved in specific volumes of Lidocaine HCI 1% injection or Water for injection
- Administration over 2-4 minutes for Intramuscular or Intravenous injection
Interaction
No drug interactions have been reported
Contraindications
Not to be given to patients with hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis
Pregnancy & Lactation
Safety in human pregnancy not established; caution in lactating mothers
Precautions & Warnings
- Anaphylactic shock possible
- Shadows suggesting sludge in gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
Must not be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
No specific antidote; symptomatic treatment
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place below 30°C, away from light & moisture; Keep out of the reach of children