Tribac 500 mg/vial (IV Injection)

500 mg vial: ৳ 120.00

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms.

Dosage

  • Usual dose for adults: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum dose for adults: 4 gm/day
  • Usual dose for Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Duration of therapy: 4 to 14 days

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Intramuscular Injection: 250 mg or 500 mg Ceftriaxone dissolved in Lidocaine HCI 1% injection
  • Intravenous Injection: 250 mg or 500 mg Ceftriaxone dissolved in Water for injection

Interaction

No drug interactions have been reported

Contraindications

Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects including diarrhea, nausea and vomiting
  • Cutaneous reactions including rash, pruritus, urticaria
  • Hematologic reactions including eosinophilia, thrombocytopenia, leucopenia
  • Hepatic reactions including elevations of liver enzymes
  • CNS reactions including nervousness, confusion, sleep disturbances

Pregnancy & Lactation

Safety in human pregnancy has not been established, caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Anaphylactic shock cannot be ruled out
  • Biliary sludge detected by sonograms of the gallbladder
  • Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

Tribac must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote, treatment of overdosage should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Vial store in a cool, dry place (below 30° C), away from light & moisture. Keep out of the reach of children

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