Tribac 1 gm/vial (IV Injection)

1 gm vial: ৳ 190.00

Medicine Details

Category	Details
Generic	Ceftriaxone sodium
Company	Globe pharmaceuticals ltd
Also available as	Tribac 250 mg injection Tribac 500 mg injection Tribac 250 mg injection Tribac 500 mg injection Tribac 2 gm injection

Indications

Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery

Pharmacology

Ceftriaxone is a 3rd generation broad-spectrum parenteral cephalosporin antibiotic with potent bactericidal activity against a wide range of Gram-positive and Gram-negative organisms. It kills bacteria by interfering with the synthesis of the bacterial cell wall. It has a high degree of stability in the presence of beta lactamases and a relatively long plasma elimination half-life of about 6 to 9 hours.

Dosage

Adult:
- 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Maximum dose: 4 gm/day
Uncomplicated gonococcal infections: 250 mg IM as a single dose
Surgical prophylaxis: 1 g IV as a single dose 30 to 120 minutes before surgery
Infants and Children (01 month or older): 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)

Administration

Intramuscular Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Lidocaine HCI 1% injection
Intravenous Injection: 250 mg or 500 mg Ceftriaxone should be dissolved in Water for injection

Interaction

No drug interactions reported

Contraindications

Should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

Gastro-intestinal effects
Cutaneous reactions
Hematologic reactions
Hepatic reactions
CNS reactions
Local phlebitis

Pregnancy & Lactation

Safety in human pregnancy has not been established. Caution should be exercised when administered to a lactating mother

Precautions & Warnings

Anaphylactic shock
Gallbladder issues
Blood picture should be checked during prolonged treatment

Use in Special Populations

Must not be given to neonates if premature and newborn up to 28 days of age

Overdose Effects

No specific antidote. Treatment of overdosage should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture. Keep out of reach of children