Tribac 2 gm/vial (IV Injection)

2 gm vial: ৳ 300.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Globe pharmaceuticals ltd
Also available as
Tribac 250 mg injection Tribac 500 mg injection Tribac 250 mg injection Tribac 500 mg injection Tribac 1 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
  • Interferes with the synthesis of the bacterial cell wall
  • High degree of stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life of about 6 to 9 hours
  • Not metabolized in the body
  • Highly protein bound (95%)

Dosage

  • Usual dose is 1 to 2 gm by intravenous or intramuscular administration once a day
  • Different dosage for adults, infants, and children
  • Uncomplicated gonococcal infections dosage: 250 mg IM as a single dose
  • Surgical prophylaxis dosage: 1 g IV as a single dose 30 to 120 minutes before surgery
  • Duration of therapy: Continue for more than 2 days after signs and symptoms of infection have disappeared

Administration

  • Preparation of Solutions for Intramuscular / Intravenous Injections
  • Injection should be administered over 2-4 minutes
  • Preparation specifications for Intramuscular and Intravenous Injections

Interaction

  • No drug interactions reported

Contraindications

  • Patients with a history of hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis

Pregnancy & Lactation

  • Safety in human pregnancy has not been established
  • Cautious use in lactating mothers

Precautions & Warnings

  • Anaphylactic shock
  • Rare cases of shadows suggesting sludge in the gallbladder
  • Blood picture should be checked at regular intervals during prolonged treatment

Use in Special Populations

  • Must not be given to neonates if premature and newborn (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Treatment of overdosage should be symptomatic

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Keep away from light and moisture
  • Keep out of the reach of children

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