Trimax 1 gm/vial (IV Injection)

1 gm vial: ৳ 160.00

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Pharmasia limited
Also available as
Trimax 250 mg injection Trimax 500 mg injection Trimax 1 gm injection Trimax 500 mg injection Trimax 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • 3rd generation broad-spectrum parenteral cephalosporin antibiotic
  • Potent bactericidal activity
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life of about 6 to 9 hours
  • Highly protein bound (95%)
  • Not metabolized in the body
  • Excretion in urine and bile

Dosage

  • Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Maximum dose: 4 gm/day for adult
  • Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Duration of therapy: 4 to 14 days

Administration

  • For Intramuscular Injection: 250 mg or 500 mg Ceftriaxone dissolved in Lidocaine HCI 1% injection
  • For Intravenous Injection: 250 mg or 500 mg Ceftriaxone dissolved in Water for injection

Interaction

No drug interactions reported

Contraindications

Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis following intravenous administration

Pregnancy & Lactation

  • Safety in human pregnancy not established
  • Caution advised during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Monitoring blood picture during prolonged treatment

Use in Special Populations

Avoid use in premature and newborn (up to 28 days of age)

Overdose Effects

No specific antidote, treatment should be symptomatic

Therapeutic Class

Third generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture

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