Triphin 250 mg/vial (IM Injection)

250 mg vial: ৳ 80.24

Medicine Details

Category Details
Generic Ceftriaxone sodium
Company Ziska pharmaceuticals ltd
Also available as
Triphin 500 mg injection Triphin 1 gm injection Triphin 250 mg injection Triphin 500 mg injection Triphin 1 gm injection Triphin 2 gm injection

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum parenteral cephalosporin antibiotic
  • Bactericidal activity against Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life
  • Not metabolized in the body
  • Excretion via urine and bile/feces
  • High protein binding

Dosage

  • Usual adult dose of 1 to 2 gm by intravenous or intramuscular administration once a day
  • Different doses for specific infections
  • Maximum daily doses for various conditions
  • Usual infant and children doses by weight
  • Duration of therapy guidelines

Administration

  • Preparation of solutions for intramuscular and intravenous injections
  • Specific dosages for different injection types
  • Recommended administration duration
  • Fresh solution potency duration

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastro-intestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis after intravenous administration

Pregnancy & Lactation

  • Safety not established in pregnancy
  • Caution during lactation due to excretion in human milk

Precautions & Warnings

  • Anaphylactic shock risk
  • Sonogram findings relating to the gallbladder
  • Blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid in premature and newborn neonates (up to 28 days of age)

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store vials below 30°C, away from light and moisture

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