Trizon 500 mg/vial (IM Injection)
500 mg vial: ৳ 130.39
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity
- Interferes with synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Relatively long plasma elimination half-life
- Not metabolized in the body
- Highly protein bound (95%)
Dosage
- Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
Administration
- Preparation of Solutions for Intramuscular / Intravenous Injections
- Dissolution in Lidocaine HCI or Water for injection
- Recommended administration over 2-4 minutes
- Patient tolerance test before treatment
Interaction
- No reported drug interactions
Contraindications
- Patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects including diarrhea, nausea, vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT
- CNS reactions including nervousness, confusion, headache
- Local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution in lactating mothers
Precautions & Warnings
- Risk of anaphylactic shock
- Potential gallbladder sludge with prolonged therapy
- Blood picture checks during prolonged treatment
Use in Special Populations
- Avoid in premature and newborn neonates
Overdose Effects
- No specific antidote. Symptomatic treatment.
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store in a cool, dry place below 30°C
- Away from light & moisture
- Keep out of the reach of children