Trizon 1 gm/vial (IV Injection)

1 gm vial: ৳ 190.58

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Potent bactericidal activity
  • Wide range of Gram-positive and Gram-negative organisms
  • Interferes with bacterial cell wall synthesis
  • High stability in the presence of beta lactamases
  • Relatively long plasma elimination half-life
  • Not metabolized in the body

Dosage

  • Adult dosage: 1-2 gm once daily
  • Maximum dose: 4 gm/day
  • Infants and children dosage: 50-75 mg/kg once daily
  • Maximum dose: 2 gm/day
  • Duration of therapy: 4-14 days

Administration

  • Preparation for Intramuscular Injection
  • Preparation for Intravenous Injection
  • Recommended administration time and concentration range
  • Patient tolerance test recommendation
  • Solution stability guidelines

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Local phlebitis after intravenous administration

Pregnancy & Lactation

  • Safety not established in human pregnancy
  • Caution in lactating mothers due to excretion in human milk

Precautions & Warnings

  • Potential for anaphylactic shock
  • Detected shadows in gallbladder
  • Regular blood picture checks during prolonged treatment

Use in Special Populations

  • Avoid in premature newborns up to 28 days of age

Overdose Effects

  • No specific antidote
  • Symptomatic treatment recommended

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store vials below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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