Trizon 2 gm/vial (IV Injection)
2 gm vial: ৳ 300.90
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Bactericidal activity against a wide range of Gram-positive and Gram-negative organisms
- Kills bacteria by interfering with the synthesis of the bacterial cell wall
- Stable in the presence of beta lactamases
- Relatively long plasma elimination half-life (6 to 9 hours)
Dosage
- Adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
- Usual duration of therapy: 4 to 14 days for most infections
Administration
- Intramuscular or intravenous administration
- Preparation of solutions for intramuscular/intravenous injections
Interaction
No drug interactions reported
Contraindications
Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastrointestinal effects including diarrhea, nausea, vomiting
- Cutaneous reactions including rash, pruritus, urticaria
- Hematologic reactions including eosinophilia, thrombocytopenia
- Hepatic reactions including elevations of SGOT or SGPT
- CNS reactions including nervousness, confusion, headache
- Rare occurrence of local phlebitis following intravenous administration
Pregnancy & Lactation
Not established in human pregnancy, caution in lactating mothers
Precautions & Warnings
- Possibility of anaphylactic shock
- Rare cases of shadows suggesting sludge in gallbladder
- Regular blood picture checks during prolonged treatment
Use in Special Populations
Not to be given to neonates if premature or under 28 days of age
Overdose Effects
No specific antidote, symptomatic treatment
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Store in a cool, dry place below 30°C, away from light and moisture