Winner 500 mg/vial (IM Injection)

500 mg vial: ৳ 120.45

Medicine Details

Indications

  • Lower respiratory tract infections
  • Acute Bacterial Otitis Media
  • Skin and skin structure infections
  • Urinary tract infections
  • Gonorrhea
  • Bacterial Septicemia
  • Bone and joint infections
  • Meningitis
  • Prevention of postoperative infections
  • Perioperative prophylaxis of infections associated with surgery

Pharmacology

  • Broad-spectrum antibiotic
  • Potent bactericidal activity
  • Kills bacteria by interfering with cell wall synthesis
  • High stability in the presence of beta lactamases
  • Long plasma elimination half-life
  • Not metabolized in the body
  • Excretion in urine and feces

Dosage

  • Adult dosage: 1 to 2 gm by intravenous or intramuscular administration once a day
  • Pediatric dosage: 50 to 75 mg/kg intravenous or intramuscular administration once a day
  • Various dosage for different infections
  • Maximum daily doses for different infections
  • Duration of therapy

Administration

  • Preparation of solutions for intramuscular and intravenous injections
  • Recommended test dose for patient tolerance
  • Recommended concentration for intravenous injection

Interaction

  • No reported drug interactions

Contraindications

  • Hypersensitivity to cephalosporin antibiotics

Side Effects

  • Gastrointestinal effects
  • Cutaneous reactions
  • Hematologic reactions
  • Hepatic reactions
  • CNS reactions
  • Rare occurrence of local phlebitis following intravenous administration

Pregnancy & Lactation

  • Not established as safe in human pregnancy
  • Excretion in human milk
  • Caution advised during lactation

Precautions & Warnings

  • Risk of anaphylactic shock
  • Monitoring of blood picture during prolonged treatment
  • Potential reversible condition related to gallbladder

Use in Special Populations

  • Avoid use in neonates if premature or newborn

Overdose Effects

  • No specific antidote
  • Symptomatic treatment

Therapeutic Class

  • Third generation Cephalosporins

Storage Conditions

  • Store in a cool, dry place
  • Keep away from light and moisture
  • Keep out of reach of children

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