Winner 1 gm/vial (IV Injection)
1 gm vial: ৳ 180.68
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Biopharma limited |
| Also available as |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity
- Interferes with bacterial cell wall synthesis
- Stable in the presence of beta lactamases
- Long plasma elimination half-life
- Highly protein bound (95%)
- Metabolized in urine and bile
- Not metabolized in the body
Dosage
- Usual dose for adults: 1-2 gm by IV or IM once a day
- Dosage for various infections and conditions
- Maximum dose for adults: 4 gm/day
- Usual dose for infants and children: 50-75 mg/kg IV or IM once a day
- Maximum dose for infants and children: 2 gm/day
- Duration of therapy: 4-14 days
Administration
- Preparation of solutions for intramuscular / intravenous injections
- Use of Lidocaine HCI 1% injection for intramuscular injection
- Use of Water for injection for intravenous injection
- Recommended injection administration periods and concentrations
- Patient tolerance test before treatment
- Solution stability at different temperatures
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Well tolerated but may cause gastrointestinal effects
- May cause cutaneous reactions and hematologic reactions
- Rare occurrence of local phlebitis following intravenous administration
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution in lactating mothers
Precautions & Warnings
- Potential for anaphylactic shock
- Rare occurrence of gallbladder sludge
- Regular blood picture checks during prolonged treatment
Use in Special Populations
- Not recommended for neonates if premature
Overdose Effects
- No specific antidote
- Symptomatic treatment
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store vial in cool, dry place (below 30°C)
- Keep away from light & moisture
- Keep out of the reach of children