Calbeta 5 mg+50 mg (Tablet)
Unit Price: ৳ 7.50 (3 x 10: ৳ 225.00)
Strip Price: ৳ 75.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate atenolol |
Company | Unimed unihealth pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Amlodipine is a dihydropyridine calcium antagonist
- Amlodipine is a peripheral vasodilator
- Atenolol is a cardioselective beta-blocker
- Atenolol causes a reduction in blood pressure by lowering cardiac output
- Atenolol decreases the plasma renin activity and sympathetic outflow from CNS
Dosage & Administration
- Recommended dosage is Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily as advised by physicians
- Dosage should be individualized
Interaction
- Atenolol reduces the clearance of disopyramide by 20%
- Ampicillin at doses of 1 gm and above may reduce Atenolol levels
- Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy should outweigh potential fetal risk
- Not recommended for nursing mothers
Precautions & Warnings
- Caution in patients with airway obstruction
- Caution in patients with renal impairment
- Caution in patients with severe liver damage
- Patients should be warned against stopping the drug suddenly
Overdose Effects
- Hypotension
- Congestive cardiac failure
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children
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