Ceftipime 2 gm/vial (IV Injection)

2 gm vial: ৳ 1,104.15

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Renata limited
Also available as
Ceftipime 500 mg injection Ceftipime 1 gm injection

Indications

  • Treatment of Pneumonia (moderate to severe)
  • Treatment of Febrile Neutropenia
  • Treatment of Urinary Tract Infections
  • Treatment of Skin and Skin Structure Infections
  • Treatment of Intra-abdominal Infections

Pharmacology

  • Bactericidal action
  • Disruption of peptidoglycan synthesis
  • Mode of action similar to penicillins
  • Inhibition of transpeptidation
  • Importance in Gram-positive organisms

Dosage & Administration

  • Intravenous administration
  • Dosage for different types of infections
  • Duration of treatment
  • Instructions for administration
  • Caution for high risk and neutropenic patients

Interaction

  • Monitoring of renal function
  • Potential nephrotoxicity and ototoxicity
  • Potential nephrotoxicity with diuretics

Contraindications

  • Immediate hypersensitivity reactions to cephalosporins
  • Immediate hypersensitivity reactions to penicillin
  • Contraindicated in certain antibiotic classes

Side Effects

  • Potential adverse reactions
  • Possible hypersensitivity reactions
  • Adverse reactions in specific patient groups

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution for use during pregnancy
  • Low concentration in breast milk
  • Caution for nursing women

Precautions & Warnings

  • Appropriate use in bacterial infections
  • Risk of drug-resistant bacteria
  • Overgrowth of non-susceptible microorganisms
  • Monitoring prothrombin activity
  • Caution for patients with gastrointestinal disease
  • Effect of arginine on glucose metabolism

Use in Special Populations

  • Pediatric Use
  • Geriatric Use
  • Impaired Hepatic Function
  • Impaired Renal Function
  • Dose adjustment for renal impairment

Overdose Effects

  • Observation and supportive treatment for overdose
  • Recommendation for hemodialysis in renal insufficiency
  • Symptoms of overdose

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Intravenous and intramuscular reconstitution
  • Compatibility with IV infusion fluids
  • Instructions for reconstitution for different vial sizes

Storage Conditions

  • Expiration date
  • Storage precautions
  • Dispensing on prescription only

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