Forgen 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 550.00

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Aristopharma ltd
Also available as
Forgen 500 mg injection Forgen 2 gm injection

Indications

  • Pneumonia (moderate to severe)
  • Febrile Neutropenia
  • Uncomplicated and Complicated Urinary Tract Infections (including pyelonephritis)
  • Uncomplicated Skin and Skin Structure Infections
  • Complicated Intra-abdominal Infections (used in combination with metronidazole)

Pharmacology

  • Bactericidal action
  • Mode of action similar to other beta-lactam antibiotics
  • Disruption of peptidoglycan layer synthesis
  • Importance in Gram-positive organisms

Dosage & Administration

  • Intravenous administration
  • Various dosages for different infections
  • Administration duration specified for different infections
  • Notes on route of administration for specific infections

Interaction

  • Monitoring of renal function
  • Potential nephrotoxicity and ototoxicity with aminoglycosides
  • Reported nephrotoxicity with cephalosporins and potent diuretics

Contraindications

  • Immediate hypersensitivity to cefepime or cephalosporin class of antibiotics
  • Contraindication in patients with penicillin or other betalactum antibiotic hypersensitivity

Side Effects

  • Possible adverse reactions

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution in use during pregnancy
  • Excretion in human breast milk
  • Caution when administered to nursing women

Precautions & Warnings

  • Appropriate use in proven or strongly suspected bacterial infection
  • Risk of drug-resistant bacteria
  • Ensuring evaluation of patient's condition
  • Association with fall in prothrombin activity
  • Caution in patients with renal or hepatic impairment
  • Prescription caution for individuals with gastrointestinal disease
  • Potential effect of arginine on glucose metabolism and serum potassium levels

Use in Special Populations

  • Pediatric use with maximum recommended dosage
  • Special considerations in geriatric patients and individuals with impaired renal function or hepatic function

Overdose Effects

  • Observation and supportive treatment for overdose
  • Recommendation for hemodialysis in renal insufficiency
  • Reported symptoms of overdose

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Administration via intravenous and intramuscular routes
  • Compatibility with various diluents
  • Specific diluent amounts for different vials

Storage Conditions

  • Expiry date
  • Storage guidelines
  • Dispensing requirement

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