Gen4 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 555.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Title
- Gen4
Categories
- Medicine
- Pharmaceuticals
Description
- Fourth generation cephalosporin indicated for the treatment of various infections caused by susceptible strains of microorganisms.
Indications
- Treatment of pneumonia (moderate to severe)
- Treatment of febrile neutropenia
- Treatment of urinary tract infections (complicated and uncomplicated)
- Treatment of skin and skin structure infections
- Treatment of intra-abdominal infections (used in combination with metronidazole)
Pharmacology
- Bactericidal action
- Disruption of peptidoglycan layer synthesis in bacterial cell walls
- Mode of action similar to other beta-lactam antibiotics
Dosage & Administration
- Administered intravenously over approximately 30 minutes
- Specific dosage for various infections as per severity level and causative microorganisms
Interaction
- Monitoring of renal function when administered with aminoglycosides
- Potential nephrotoxicity and ototoxicity with aminoglycoside antibiotics
Contraindications
- Immediate hypersensitivity reactions to cefepime or cephalosporin class of antibiotics
- Hypersensitivity to penicillin or other betalactum antibiotics
Side Effects
- Immediate hypersensitivity reactions
- Potential for overgrowth of non-susceptible microorganisms with prolonged use
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in human breast milk in very low concentrations
- Caution advised during lactation
Precautions & Warnings
- Prescription only in presence of proven or strongly suspected bacterial infection
- Monitoring of patient's condition during prolonged use
- Association with fall in prothrombin activity
- Caution in patients with history of gastrointestinal disease
- Effects of arginine on glucose metabolism and serum potassium
Use in Special Populations
- Pediatric use up to 16 years with maximum recommended dose
- Caution in geriatric patients with renal insufficiency
- No dose adjustment for impaired hepatic function
- Dose adjustment for impaired renal function
Overdose Effects
- Careful observation and supportive treatment for patients
- Recommendation of hemodialysis in case of renal insufficiency
- Symptoms include encephalopathy, myoclonus, seizures, and neuromuscular excitability
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Intravenous and intramuscular administration
- Compatibility with various diluents and IV infusion fluids
- Specific details for reconstitution of different vial strengths
Storage Conditions
- Expiry date adherence
- Medicine safety around children
- Dispensing only on registered physician's prescription