Pime-4 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 302.04

Medicine Details

Category	Details
Generic	Cefepime hydrochloride
Company	Aci limited
Also available as	Pime 4 1 gm injection

Indications

Pneumonia (moderate to severe)
Febrile Neutropenia
Uncomplicated and Complicated Urinary Tract Infections
Uncomplicated Skin and Skin Structure Infections
Complicated Intra-abdominal Infections

Pharmacology

Bactericidal mode of action
Disrupts synthesis of peptidoglycan layer

Dosage & Administration

Route of administration: Intravenous
Recommended dosage for different infections
Special note for IM route of administration

Interaction

Increased potential of nephrotoxicity
Interaction with potent diuretics

Contraindications

Immediate hypersensitivity to cefepime or cephalosporin class of antibiotics

Side Effects

Immediate hypersensitivity reactions

Pregnancy & Lactation

Pregnancy Category B
Excretion in breast milk
Caution in nursing women

Precautions & Warnings

Use only for proven bacterial infections
Risk of drug-resistant bacteria
Prolonged use may result in overgrowth of non-susceptible microorganisms
Association with fall in prothrombin activity
Caution in gastrointestinal disease
Effects of arginine on glucose metabolism and serum potassium

Use in Special Populations

Pediatric use: Maximum dose, recommended dosage
Geriatric use: Adverse events, dose selection, and monitoring
Impaired hepatic function: No adjustment necessary
Impaired renal function: Dose adjustment

Overdose Effects

Observation and supportive treatment
Recommendation for hemodialysis
Symptoms of overdose

Therapeutic Class

Fourth-generation Cephalosporins

Reconstitution

IV and IM administration instructions
Compatibility with different IV fluids and diluents
Specific instructions for different vial sizes

Storage Conditions

Expiry date, Keep out of reach of children, Prescription required for dispensing

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