Pime-4 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 553.73
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Aci limited |
| Also available as |
Indications
- Treatment of moderate to severe pneumonia
- Treatment of febrile neutropenia
- Treatment of uncomplicated and complicated urinary tract infections
- Treatment of uncomplicated skin and skin structure infections
- Treatment of complicated intra-abdominal infections
Pharmacology
- Bactericidal nature
- Mode of action disruption of peptidoglycan layer
- Similar mode of action to penicillins
- Disruption of synthesis of bacterial cell walls
Dosage & Administration
- Intravenous administration over 30 minutes
- Various dosages for different infections
- Duration of treatment for different infections
- Notes on administration routes
- Caution for specific patient groups
Interaction
- Monitoring renal function during aminoglycosides administration
- Potential nephrotoxicity and ototoxicity
- Nephrotoxicity with cephalosporins and diuretics
Contraindications
- Immediate hypersensitivity reactions to cefepime or cephalosporins
- Contraindicated in certain antibiotic allergies
Side Effects
- Potential adverse reactions
- Allergic reactions
- Possible contraindications
Pregnancy & Lactation
- Pregnancy Category B
- Caution in use during pregnancy
- Excretion in breast milk
- Nursing woman caution
Precautions & Warnings
- Appropriate prescribing for bacterial infection
- Potential overgrowth of non-susceptible microorganisms
- Monitoring patient's condition
- Association with fall in prothrombin activity
- Caution in individuals with gastrointestinal disease
- Effects on glucose metabolism and serum potassium
Use in Special Populations
- Pediatric use and dosage
- Geriatric use and potential adverse events
- Impaired hepatic and renal function adjustments
- Dose adjustment for impaired renal function
Overdose Effects
- Observation and supportive treatment for overdosed patients
- Hemodialysis for renal insufficiency
- Symptoms of overdose
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Administration methods
- Compatibility with IV fluids and diluents
- Instructions for vial reconstitution
Storage Conditions
- Expiry date
- Keep out of reach of children
- Dispensing on physician prescription