Calock Plus 5 mg+50 mg (Tablet)

Unit Price: ৳ 4.50 (42's pack: ৳ 189.00)

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Post Ml patients
  • Refractory angina pectoris
  • Nitrate therapy failure

Pharmacology

  • Fixed-dose combination of Amlodipine and Atenolol
  • Dihydropyridine calcium antagonist
  • Cardioselective beta-blocker
  • Reduction in peripheral vascular resistance
  • Reduction in blood pressure
  • Reduction in cardiac demand

Dosage & Administration

  • Recommended dosage: 5/25 mg once daily
  • Maximum dosage: 5/25 mg two tablets daily
  • Individualized dosage

Interaction

  • Disopyramide: Reduction in clearance by 20%
  • Negative inotropic effects on the heart
  • Ampicillin: Reduction in Atenolol levels
  • Oral antidiabetics and insulin: Tissue sensitivity reduction

Contraindications

  • Hypersensitivity to either component
  • Sinus bradycardia
  • Second and higher degrees of heart block
  • Cardiogenic shock
  • Hypotension
  • Congestive heart failure
  • Poor left ventricular function

Side Effects

  • Fatigue
  • Headache
  • Edema
  • Nausea
  • Drowsiness
  • Anxiety
  • Depression

Pregnancy & Lactation

  • Use during pregnancy if benefits outweigh risks
  • Avoid use by nursing mothers

Precautions & Warnings

  • Bronchospasm caution
  • Renal impairment caution
  • Hepatic impairment caution
  • Gradual drug withdrawal

Overdose Effects

  • Hypotension
  • Congestive cardiac failure
  • Unabsorbed drug removal methods
  • Symptomatic treatment

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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