Tupime 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 551.65

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Kemiko pharmaceuticals ltd

Indications

  • Pneumonia (moderate to severe)
  • Febrile Neutropenia
  • Uncomplicated and Complicated Urinary Tract Infections (including pyelonephritis)
  • Uncomplicated Skin and Skin Structure Infections
  • Complicated Intra-abdominal Infections
  • Viridans group streptococci infections

Pharmacology

  • Bactericidal mode of action
  • Disruption of peptidoglycan layer synthesis
  • Similar mode of action as penicillins
  • Facilitation by penicillin binding proteins

Dosage & Administration

  • Intravenous administration
  • Dosage based on infection severity
  • Duration of treatment
  • Note on route of administration

Interaction

  • Monitoring of renal function
  • Potential nephrotoxicity and ototoxicity
  • Concomitant administration with aminoglycosides

Contraindications

  • Immediate hypersensitivity reactions

Side Effects

  • Immediate hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category B
  • Excretion in breast milk
  • Caution for nursing women

Precautions & Warnings

  • Prescribing without proven or suspected bacterial infection
  • Prolonged use leading to overgrowth of non-susceptible microorganisms
  • Association with fall in prothrombin activity
  • Use with caution in individuals with gastrointestinal disease
  • Effect of arginine on glucose metabolism

Use in Special Populations

  • Pediatric use
  • Geriatric use
  • Impaired hepatic function
  • Impaired renal function
  • Dose adjustment in patients with impaired renal function

Overdose Effects

  • Observation and supportive treatment
  • Recommendation for hemodialysis

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Intravenous injection
  • Compatible with IV infusion fluids
  • Intramuscular administration
  • Amount of diluent to be added for different vial sizes

Storage Conditions

  • Expiry date
  • Keep out of reach of children
  • Dispensing on prescription only

Related Brands