Unipim 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 301.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Drug international ltd |
| Also available as |
Title
- Unipim 4th Generation Cephalosporin Antibiotic
Categories
- Medicine
- Antibiotic
- Cephalosporin
Indications
- Treatment of moderate to severe pneumonia caused by specific microorganisms
- Empiric treatment for febrile neutropenic patients
- Treatment of uncomplicated and complicated urinary tract infections
- Treatment of uncomplicated skin and skin structure infections
- Treatment of complicated intra-abdominal infections (in combination with metronidazole)
Pharmacology
- Bactericidal action
- Disruption of peptidoglycan layer synthesis in bacterial cell walls
- Similar mode of action to other beta-lactam antibiotics
Dosage & Administration
- Administered intravenously over approximately 30 minutes
- Dosage varies based on the type and severity of the infection
Interaction
- Monitoring of renal function when administered with aminoglycosides
- Potential nephrotoxicity and ototoxicity with aminoglycoside antibiotics
- Nephrotoxicity risk with concomitant administration of other cephalosporins and potent diuretics
Contraindications
- Immediate hypersensitivity to cefepime or cephalosporin class of antibiotics
- Hypersensitivity to penicillin or other betalactum antibiotics
Side Effects
- Possible immediate hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in human breast milk in very low concentrations
Precautions & Warnings
- Avoid prescribing in the absence of a proven or strongly suspected bacterial infection
- Potential overgrowth of non-susceptible microorganisms with prolonged use
- Association with a fall in prothrombin activity
- Caution in individuals with a history of gastrointestinal disease
- Potential glucose metabolism alteration with arginine administration
Use in Special Populations
- Pediatric use up to 16 years with maximum dose restriction
- Geriatric use and risk of serious adverse events in renal insufficiency
- Renal function adjustment in impaired renal function patients
Overdose Effects
- Careful observation and supportive treatment for patients receiving overdose
- Recommendation for hemodialysis in the presence of renal insufficiency
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Intravenous and intramuscular administration instructions
- Compatibility with specific IV infusion fluids and diluents
- List of amounts of diluent to be added for different dosage vials
Storage Conditions
- Dispensing only on prescription of a registered physician
- Expiry date check
- Keep out of reach of children