Ximepime 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 550.00

Medicine Details

Category Details
Generic Cefepime hydrochloride
Company Globe pharmaceuticals ltd
Also available as
Ximepime 500 mg injection Ximepime 2 gm injection

Title

  • Ximepime (Cefepime) Injection

Categories

  • Pharmaceuticals
  • Medicine
  • Antibiotics

Description

  • Cefepime effectively treats various bacterial infections
  • IV administration over approximately 30 minutes
  • Compatible with various IV infusion fluids
  • Prolonged use may result in overgrowth of non-susceptible microorganisms
  • Fourth generation Cephalosporin
  • Do not use later than the date of expiry
  • To be dispensed only on the prescription of a registered physician

Indications

  • Treatment of moderate to severe pneumonia caused by specific microorganisms
  • Empiric treatment of febrile neutropenic patients
  • Treatment of complicated urinary tract infections, including pyelonephritis
  • Treatment of uncomplicated skin and skin structure infections
  • Treatment of complicated intra-abdominal infections (in combination with metronidazole)

Pharmacology

  • Cephalosporins are bactericidal
  • Disrupts the synthesis of the peptidoglycan layer of bacterial cell walls

Dosage & Administration

  • Specific dosages for different types of infections
  • IV administration recommended
  • Caution for patients with diminished renal or hepatic function

Interaction

  • Monitor renal function when administering high doses with aminoglycosides
  • Risk of nephrotoxicity with potent diuretics

Contraindications

  • Immediate hypersensitivity reactions to cefepime or cephalosporin class of antibiotics
  • Contraindicated in patients allergic to penicillin or other beta-lactam antibiotics

Side Effects

  • Potential for hypersensitivity reactions

Pregnancy & Lactation

  • Pregnancy Category B
  • Excreted in low concentrations in human breast milk

Precautions & Warnings

  • Avoid prescribing in the absence of proven or strongly suspected bacterial infection
  • Close monitoring for overgrowth of non-susceptible microorganisms
  • Associated with a fall in prothrombin activity

Use in Special Populations

  • Maximum dose for pediatric patients should not exceed the recommended adult dose
  • Caution in geriatric patients with renal insufficiency
  • No dose adjustment for patients with impaired hepatic function
  • Dose adjustment for patients with impaired renal function

Overdose Effects

  • Careful observation and supportive treatment for overdose patients
  • Hemodialysis recommended in the presence of renal insufficiency

Therapeutic Class

  • Fourth generation Cephalosporins

Reconstitution

  • Instructions for IV and IM administration
  • Compatibility with various IV infusion fluids and diluents

Storage Conditions

  • Do not use later than the date of expiry
  • To be dispensed only on the prescription of a registered physician

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