Magnova 500 mg/vial (IM/IV Injection)
500 mg vial: ৳ 300.90
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Orion pharma ltd |
| Also available as |
Indications
- Treatment of moderate to severe pneumonia
- Treatment of febrile neutropenia
- Treatment of urinary tract infections
- Treatment of skin and skin structure infections
- Treatment of complicated intra-abdominal infections
- Empiric therapy for febrile neutropenic patients
Pharmacology
- Bactericidal mode of action
- Disruption of peptidoglycan layer synthesis
- Similar mode of action to penicillins
- Inhibition of transpeptidases
Dosage & Administration
- Intravenous administration over approximately 30 minutes
- Dosage adjustment based on infection severity
- Different dosages for different types of infections
Interaction
- Risk of nephrotoxicity with aminoglycosides
- Potential nephrotoxicity with diuretics
Contraindications
- Immediate hypersensitivity to cefepime or cephalosporins
- Hypersensitivity to penicillin or betalactam antibiotics
Side Effects
- Immediate hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in breast milk
- Caution for nursing women
Precautions & Warnings
- Avoid use in absence of bacterial infection
- Risk of overgrowth of non-susceptible microorganisms
- Association with fall in prothrombin activity
- Caution in individuals with gastrointestinal disease
Use in Special Populations
- Maximum dose for pediatric patients
- Adverse events in geriatric patients with renal insufficiency
- Excretion by kidney
- Adjustment for impaired renal function
Overdose Effects
- Observation and supportive treatment for overdose
- Recommendation for hemodialysis in renal insufficiency
- Symptoms of overdose
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Intravenous and intramuscular administration
- Compatibility with different IV infusion fluids and diluents
- Reconstitution details for different vial sizes
Storage Conditions
- Expiry date
- Keep out of reach of children
- Dispensation only on prescription