Camlodin Plus 5 mg+25 mg (Tablet)
Unit Price: ৳ 6.00 (3 x 10: ৳ 180.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Amlodipine is a dihydropyridine calcium antagonist
- Amlodipine acts as a peripheral vasodilator
- Atenolol is a cardioselective beta-blocker
- Atenolol causes reduction in blood pressure
- Atenolol reduces myocardial oxygen demand
Dosage & Administration
- Recommended dosage: Amlodipine and Atenolol 5/25 mg tablet once daily
- Possible dosage increase as advised by physicians
- Dosage should be individualized
Interaction
- Atenolol reduces the clearance of disopyramide by 20%
- Additive negative inotropic effects with disopyramide
- Ampicillin may reduce Atenolol levels at 1 gm and above
- Beta-blockers may decrease tissue sensitivity to insulin
- Atenolol has less potential for insulin inhibition
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Well tolerated combination
- Side effects include fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Use during pregnancy if benefit outweighs fetal risk
- Not recommended for nursing mothers
Precautions & Warnings
- Use with caution in patients with airway obstruction
- Can be used in patients with renal impairment
- Caution if creatinine clearance is less than 30 ml/min
- Caution in patients with severe liver damage
- Patients should be warned against stopping the drug suddenly
Overdose Effects
- Hypotension
- Congestive cardiac failure
- Gastric lavage or administration of activated charcoal for unabsorbed drugs
- Symptomatic treatment suggested
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of reach of children