Iropen (500 mg+500 mg)/vial (IV Injection)

Unit Price: ৳ 1,295.00

Medicine Details

Category	Details
Generic	Imipenem cilastatin
Company	Renata limited

Indications

Lower respiratory tract infections
Urinary tract infections
Intra-abdominal infections
Gynecologic infections
Bacterial septicemia
Bone and joint infections
Skin and skin structure infections
Endocarditis

Pharmacology

Combination of Imipenem and Cilastatin
Bactericidal activity
Inhibition of cell wall synthesis
Stability in the presence of beta-lactamases
Inhibitor of betalactamases
Affinity for penicillin binding proteins

Dosage & Administration

Dosage based on pathogen susceptibility
Recommended dosage regimens for adult patients
Dosage adjustment for patients with renal impairment
Reconstitution with appropriate diluent
Intravenous infusion before administration
Maximum total daily dosage not to exceed 4g/day
Recommended Dosage in Pediatric Patients for Non-CNS Infections

Interaction

Concurrent administration with probenecid
Increased risk of generalized seizures with ganciclovir

Contraindications

Hypersensitivity to any component of this combination

Side Effects

Phlebitis
Nausea, diarrhea, vomiting
Rash, pruritus, urticaria
Pain at injection site, erythema at injection site
Fever
Hypotension
Seizures, dizziness, somnolence

Pregnancy & Lactation

Pregnancy Category C
Caution in use during pregnancy
Caution in use during nursing

Precautions & Warnings

Serious and occasionally fatal hypersensitivity reactions
Seizures and other CNS adverse reactions

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Do not use diluents containing benzyl alcohol for neonates
Reconstitution with 0.9% Sodium Chloride Injection
Variations of color do not affect potency
Storage of reconstituted solutions

Storage Conditions

Store at or below 25°C
Keep away from light and wet place
Keep out of reach of children

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