Iropen (500 mg+500 mg)/vial (IV Injection)
Unit Price: ৳ 1,295.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Imipenem cilastatin |
| Company | Renata limited |
Indications
- Lower respiratory tract infections
- Urinary tract infections
- Intra-abdominal infections
- Gynecologic infections
- Bacterial septicemia
- Bone and joint infections
- Skin and skin structure infections
- Endocarditis
Pharmacology
- Combination of Imipenem and Cilastatin
- Bactericidal activity
- Inhibition of cell wall synthesis
- Stability in the presence of beta-lactamases
- Inhibitor of betalactamases
- Affinity for penicillin binding proteins
Dosage & Administration
- Dosage based on pathogen susceptibility
- Recommended dosage regimens for adult patients
- Dosage adjustment for patients with renal impairment
- Reconstitution with appropriate diluent
- Intravenous infusion before administration
- Maximum total daily dosage not to exceed 4g/day
- Recommended Dosage in Pediatric Patients for Non-CNS Infections
Interaction
- Concurrent administration with probenecid
- Increased risk of generalized seizures with ganciclovir
Contraindications
- Hypersensitivity to any component of this combination
Side Effects
- Phlebitis
- Nausea, diarrhea, vomiting
- Rash, pruritus, urticaria
- Pain at injection site, erythema at injection site
- Fever
- Hypotension
- Seizures, dizziness, somnolence
Pregnancy & Lactation
- Pregnancy Category C
- Caution in use during pregnancy
- Caution in use during nursing
Precautions & Warnings
- Serious and occasionally fatal hypersensitivity reactions
- Seizures and other CNS adverse reactions
Therapeutic Class
- Other beta-lactam Antibiotics
Reconstitution
- Do not use diluents containing benzyl alcohol for neonates
- Reconstitution with 0.9% Sodium Chloride Injection
- Variations of color do not affect potency
- Storage of reconstituted solutions
Storage Conditions
- Store at or below 25°C
- Keep away from light and wet place
- Keep out of reach of children