Aronem 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 750.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Aci limited
Also available as
Aronem 1 gm injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Exerts bactericidal action by interfering with bacterial cell wall synthesis; potent activity against broad spectrum of bacteria

Dosage

  • Adults:
    • Usual dose: 500 mg to 1 gm intravenous administration every 8 hours
    • Varied dosages for different types of infections
  • Children:
    • Dosage based on age and severity of infection
    • Different dosages for specific conditions and age groups

Administration

Administered by intravenous infusion over approximately 15-30 minutes or as intravenous bolus

Interaction

Potential interaction with probenecid and valproic acid

Contraindications

Contraindicated in patients with hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B; caution advised during lactation

Precautions & Warnings

Discontinue if allergic reaction occurs; monitor closely in patients with hepatic disease

Use in Special Populations

  • Dosage adjustments for patients with renal impairment
  • No dosage adjustments necessary for patients with hepatic impairment
  • No dosage adjustments necessary for elderly patients unless creatinine clearance is <51 ml/min

Overdose Effects

Symptomatic treatment recommended for accidental overdose

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus Administration: Reconstitute with sterile water for injection
  • Intravenous infusion administration: May be directly constituted with a compatible infusion fluid and then further diluted with the compatible infusion fluid, as needed

Storage Conditions

Store in a cool, dry place below 30°C, away from light and moisture; keep out of the reach of children

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