Carbanem 500 mg/vial (IV Injection or Infusion)
500 mg vial: ৳ 702.11
Medicine Details
| Category | Details |
|---|---|
| Generic | Meropenem trihydrate |
| Company | Synovia pharma plc |
| Also available as |
Indications
- Pneumonia and Nosocomial Pneumonia
- Urinary Tract Infections
- Intra-abdominal Infections
- Gynaecological Infections
- Skin and Skin Structure Infections
- Meningitis
- Septicaemia
- Pulmonary infections in cystic fibrosis
- Empiric treatment for presumed infections in patients with febrile neutropenia
Pharmacology
Bactericidal action by interfering with bacterial cell wall synthesis, potent against a broad spectrum of Gram-positive and Gram-negative bacteria
Dosage
- Adults: 500 mg to 1 gm by intravenous administration every 8 hours
- Children: 10 to 40 mg/kg intravenously every 8 hours depending on type and severity of infection
Administration
- Intravenous Infusion over approximately 15-30 minutes
- Intravenous bolus (5 to 20 ml) over approximately 3-5 minutes
Interaction
Competes with Carbanem for active tubular secretion, may reduce serum valproic acid levels
Contraindications
Hypersensitivity to meropenem
Side Effects
- Inflammation
- Thrombophlebitis
- Pain at the site of injection
- Skin reactions like rash, pruritus, urticaria
- Abdominal pain
- Nausea
- Vomiting
- Diarrhea
- Headache
Pregnancy & Lactation
Pregnancy Category B, caution during lactation
Precautions & Warnings
- Discontinue in case of allergic reaction
- Careful monitoring in patients with hepatic disease
Use in Special Populations
- Dosage reduction in renal impairment
- No adjustments necessary in hepatic impairment
- No adjustments necessary in elderly patients
- Efficacy and tolerability not established in infants under 3 months
Overdose Effects
Accidental overdose could occur, treatment should be symptomatic
Therapeutic Class
Other beta-lactam Antibiotics
Reconstitution
Preparation of solution for intravenous bolus and infusion administration with compatible infusion fluids
Storage Conditions
Store in a cool, dry place below 30°C, away from light and moisture, keep out of the reach of children