Fulspec 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,320.00

Medicine Details

Category	Details
Generic	Meropenem trihydrate
Company	Acme laboratories ltd
Also available as	Fulspec 500 mg injection Fulspec 250 mg injection

Indications

Pneumonia and Nosocomial Pneumonia
Urinary Tract Infections
Intra-abdominal Infections
Gynecological Infections
Skin and Skin Structure Infections
Meningitis
Septicemia
Pulmonary infections in cystic fibrosis
Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis, potent activity against a broad spectrum of bacteria

Dosage

Adults:
- 500 mg to 1 gm by intravenous administration every 8 hours
- Specific doses for different infections
Children:
- 10 to 40 mg/kg intravenously every 8 hours
- Specific doses for different infections
- Use of adult dosage for children over 50 kg weight

Administration

Administered by intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

Competes with Probenecid for active tubular secretion, may reduce serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

Inflammation
Thrombophlebitis
Pain at the site of injection
Skin reactions like rash, pruritus, urticaria
Abdominal pain
Nausea
Vomiting
Diarrhea
Headache

Pregnancy & Lactation

Pregnancy Category B, caution advised for nursing women

Precautions & Warnings

Discontinue if allergic reaction occurs
Careful monitoring in patients with hepatic disease

Use in Special Populations

Dosage adjustments for renal impairment
No dosage adjustments for hepatic impairment
Hemodialysis patients should receive after dialysis
Efficacy and tolerability not established in infants under 3 months

Overdose Effects

Symptomatic treatment, rapid renal elimination in normal individuals, hemodialysis for subjects with renal impairment

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Specific instructions for intravenous bolus and infusion administration, compatibility with various infusion fluids, recommended use of freshly reconstituted solution

Storage Conditions

Store in a cool, dry place below 30°C, away from light and moisture, keep out of the reach of children