I-Penam 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Incepta pharmaceuticals ltd
Also available as
I penam 500 mg injection I penam 250 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action
  • Interference with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Dosage and duration determined by infection type and severity
  • Recommended daily dosage for Adults
  • Recommended daily dosage for Children
  • Dosage adjustments for renal impairment
  • Dosage adjustments for hepatic impairment

Administration

  • Intravenous infusion over 15-30 minutes
  • Intravenous bolus over 3-5 minutes

Interaction

  • Probenecid interaction
  • Reduction of serum valproic acid levels

Contraindications

  • Hypersensitivity to meropenem

Side Effects

  • Inflammation at injection site
  • Thrombophlebitis
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during nursing

Precautions & Warnings

  • Allergic reaction precautions
  • Monitoring transaminase and bilirubin levels in hepatic disease patients

Use in Special Populations

  • Dosage adjustments for renal impairment
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Symptomatic treatment
  • Rapid renal elimination in normal individuals
  • Haemodialysis for subjects with renal impairment

Therapeutic Class

  • Beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus reconstitution with sterile water for injection
  • Intravenous infusion reconstitution with compatible infusion fluid
  • Use of freshly reconstituted solution recommended

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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