Meroject 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 700.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Eskayef pharmaceuticals ltd
Also available as
Meroject 1 gm injection Meroject 250 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action
  • Interferes with bacterial cell wall synthesis
  • Potent activity against a broad spectrum of bacteria
  • High stability to all serine beta-lactamases
  • Affinity for the Penicillin Binding Proteins (PBPs)

Dosage

  • Dosage establishment based on type and severity of infection
  • Recommended daily dosage for adults and children
  • Intravenous administration
  • Dosage adjustment for renal impairment
  • Use in special populations such as elderly and children
  • Overdose effects and treatment

Administration

Intravenous infusion over approximately 15-30 minutes or as intravenous bolus

Interaction

  • Interaction with Probenecid
  • Inhibition of renal excretion
  • Reduction of serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

  • Inflammation at the site of injection
  • Thrombophlebitis
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B

Precautions & Warnings

  • Allergic reaction precautions
  • Monitoring of transaminase and bilirubin levels

Use in Special Populations

  • Dosage adjustments for renal impairment
  • No dosage adjustments for hepatic impairment
  • No dosage adjustments for elderly patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Symptomatic treatment

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

  • Preparation of solution for intravenous bolus administration
  • Preparation of solution for intravenous infusion administration
  • Compatibility with various infusion fluids
  • Potency maintenance for up to 3 hours at up to 25°C or 13 hours at up to 5°C

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture

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