Merom 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,100.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Techno drugs ltd
Also available as
Merom 500 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action interfering with bacterial cell wall synthesis

Dosage

  • Usual dose for adults: 500 mg to 1 gm every 8 hours
  • Usual dose for children: 10 to 40 mg/kg every 8 hours
  • Intra-abdominal infections: 20 mg/kg every 8 hours
  • Cystic fibrosis (4-18 years): 25-40 mg/kg every 8 hours
  • Meningitis: 40 mg/kg every 8 hours

Administration

Intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

Competes with Probenecid for active tubular secretion

Contraindications

Hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B. Caution during lactation

Precautions & Warnings

  • Allergic reaction requires discontinuation
  • Careful monitoring in patients with hepatic disease

Use in Special Populations

  • Dosage reduction in patients with renal impairment
  • Hemodialysis patients should receive after dialysis
  • No dosage adjustments in elderly unless creatinine clearance is <51 ml/min
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Symptomatic treatment for accidental overdose

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus Administration
  • Intravenous infusion administration
  • Compatibility with various infusion fluids

Storage Conditions

Store in a cool, dry place (below 30°C), away from light & moisture

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