Meronix 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,200.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Novo healthcare and pharma ltd
Also available as
Meronix 500 mg injection

Indications

  • Treatment of pneumonia and nosocomial pneumonia
  • Treatment of urinary tract infections
  • Treatment of intra-abdominal infections
  • Treatment of gynecological infections
  • Treatment of skin and skin structure infections
  • Treatment of meningitis
  • Treatment of septicaemia
  • Treatment of pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action by interfering with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria
  • Effective against both Gram-positive and Gram-negative bacteria
  • Administered parenterally

Dosage

  • Recommended daily dosage for adults
  • Recommended daily dosage for children
  • Dosage adjustments for specific infections
  • Dosage adjustments based on patient's weight and age
  • Dosage adjustments for renal impairment

Administration

  • Intravenous infusion over approximately 15-30 minutes
  • Intravenous bolus over approximately 3-5 minutes
  • Administered parenterally

Interaction

  • Competes with Probenecid for active tubular secretion

Contraindications

  • Contraindicated in patients with hypersensitivity to the product

Side Effects

  • Inflammation at the site of injection
  • Thrombophlebitis
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Gastrointestinal effects like nausea, vomiting, diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution advised during nursing

Precautions & Warnings

  • Discontinue use in case of allergic reaction
  • Careful monitoring of transaminase and bilirubin levels in hepatic patients

Use in Special Populations

  • Dosage adjustments for renal impairment
  • No dosage adjustments necessary for hepatic impairment
  • Caution in use for infants under 3 months
  • Hemodialysis for hemodialysis patients

Overdose Effects

  • Symptomatic treatment for overdose
  • Haemodialysis for removal of Meronix and its metabolite

Therapeutic Class

  • Belongs to the class of Other beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus and infusion administration
  • Compatible with various infusion fluids
  • Freshly reconstituted solution is recommended
  • Maintains potency for up to 3 hours at up to 25°C or 13 hours at up to 5°C

Storage Conditions

  • Store in a cool, dry place (below 30°C)
  • Protect from light and moisture
  • Keep out of the reach of children

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