Meropen 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category	Details
Generic	Meropenem trihydrate
Company	Renata limited
Also available as	Meropen 500 mg injection Meropen 250 mg injection

Indications

Pneumonia and Nosocomial Pneumonia
Urinary Tract Infections
Intra-abdominal Infections
Gynaecological Infections
Skin and Skin Structure Infections
Meningitis
Septicaemia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis, potent activity against a broad spectrum of bacteria

Dosage

Adults: 500 mg to 1 gm by intravenous administration every 8 hours
Children: 10 to 40 mg/kg intravenously every 8 hours
Intra-abdominal infections: 20 mg/kg every 8 hours
Cystic fibrosis: Upto 2 gm every 8 hours
Meningitis: 2 gm IV every 8 hours
Febrile neutropenia: 20 mg/kg every 8 hours

Administration

Administered by intravenous infusion over approximately 15-30 minutes

Interaction

Probenecid competes with Meropen for active tubular secretion

Contraindications

Hypersensitivity to Meropenem

Side Effects

Inflammation
Thrombophlebitis
Pain at the site of injection
Skin reactions like rash, pruritus, urticaria
Abdominal pain
Nausea
Vomiting
Diarrhea
Headache

Pregnancy & Lactation

Pregnancy Category B
Caution should be exercised when administered to a nursing woman

Precautions & Warnings

Discontinue the drug if allergic reaction occurs, careful monitoring of transaminase and bilirubin levels in hepatic disease patients

Use in Special Populations

Dosage adjustment in renal impairment patients
No adjustment in elderly patients
Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Accidental overdose could occur during therapy, treatment should be symptomatic

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Preparation of solution for intravenous bolus and infusion administration

Storage Conditions

Store in a cool, dry place below 30°C, away from light & moisture

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