Ronem 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 700.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Opsonin pharma ltd
Also available as
Ronem 1 gm injection Ronem 250 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Bactericidal action
  • Interferes with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Dosage depending on type and severity of infection
  • Recommended daily dosage for adults
  • Recommended daily dosage for children
  • Duration of therapy dependent on infection type and severity

Administration

  • Intravenous infusion over 15-30 minutes
  • Intravenous bolus over 3-5 minutes

Interaction

  • Probenecid competition for active tubular secretion
  • Inhibition of renal excretion
  • Reduction of serum valproic acid levels

Contraindications

  • Hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution during nursing

Precautions & Warnings

  • Discontinue drug in case of allergic reaction
  • Careful monitoring in patients with hepatic disease

Use in Special Populations

  • Dosage adjustments for renal impairment
  • No dosage adjustments with liver function impairment
  • Use in elderly patients
  • Efficacy and tolerability in infants under 3 months

Overdose Effects

  • Accidental overdose during therapy
  • Symptomatic treatment
  • Rapid renal elimination in normal individuals
  • Haemodialysis for removal in subjects with renal impairment

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

  • Intravenous bolus Administration
  • Intravenous infusion administration
  • Compatibility with various infusion fluids
  • Storage recommendation for reconstituted solution

Storage Conditions

Cool, dry place below 30°C, away from light & moisture, keep out of reach of children

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