Intrapen 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 750.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company General pharmaceuticals ltd
Also available as
Intrapen 1 gm injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis, potent activity against a broad spectrum of bacteria

Dosage

  • Adults:
    • 500 mg to 1 gm by intravenous administration every 8 hours
    • Specific dosage for different types of infections
  • Children:
    • 10 to 40 mg/kg intravenously every 8 hours depending on type and severity of infection
    • Special dosage for different types of infections

Administration

Intravenous infusion over approximately 15-30 minutes or intravenous bolus over approximately 3-5 minutes

Interaction

Competes with Probenecid and may reduce serum valproic acid levels

Contraindications

Hypersensitivity to the product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Category B; caution during lactation

Precautions & Warnings

Discontinue in case of allergic reaction, monitor patients with hepatic disease

Use in Special Populations

  • Renal impairment: Dosage adjustment required
  • Hepatic impairment: No adjustment necessary
  • Elderly: No adjustment unless creatinine clearance is <51 ml/min
  • Children: Efficacy and tolerability not established in infants under 3 months

Overdose Effects

Accidental overdose may occur, treatment should be symptomatic

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Specific instructions for intravenous bolus and infusion administration, compatibility with various infusion fluids, recommended use timeframe

Storage Conditions

Store below 30°C, away from light & moisture, keep out of the reach of children

Related Brands