Merotrax 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 700.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Ibn sina pharmaceuticals ltd
Also available as
Merotrax 1 gm injection

Product Title and Categories

  • Merotrax - Carbapenem Antibiotic
  • Medicine
  • Antibiotics
  • Therapeutic Class: Other beta-lactam Antibiotics

Indications

  • Used for Pneumonia and Nosocomial Pneumonia
  • Treats Urinary Tract Infections
  • Effective for Intra-abdominal Infections
  • Used in Gynaecological Infections
  • Treats Skin and Skin Structure Infections
  • Effective Against Meningitis
  • Use for Septicaemia
  • Treatment for Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Meropenem is a carbapenem antibiotic for parenteral use
  • Exerts bactericidal action by interfering with bacterial cell wall synthesis
  • Shows potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Recommended daily dosage for Adults and Children
  • Different dosages for various types of infections
  • Dosage adjustment for patients with renal impairment
  • No dosage adjustment for patients with hepatic impairment
  • Special dosage considerations for children, cystic fibrosis, and meningitis

Administration

  • Administered by intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

  • Probenecid competes with Merotrax for active tubular secretion
  • Inhibits the renal excretion, increasing the elimination half-life and plasma concentration of meropenem
  • Merotrax may reduce serum valproic acid levels

Contraindications

  • Contraindicated in patients with demonstrated hypersensitivity to the product

Side Effects

  • Possible side effects such as inflammation, thrombophlebitis, pain at the site of injection, skin reactions like rash, pruritus, urticaria, abdominal pain, nausea, vomiting, diarrhea, headache

Pregnancy & Lactation

  • Pregnancy Category B - Caution advised during pregnancy
  • Caution recommended when administered to nursing women due to potential excretion in human milk

Precautions & Warnings

  • Discontinue if allergic reaction occurs
  • Careful monitoring of transaminase and bilirubin levels in patients with hepatic disease

Use in Special Populations

  • Dosage reduction in patients with renal impairment
  • No dosage adjustments necessary in patients with hepatic impairment or elderly patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Symptomatic treatment in case of accidental overdose, particularly in patients with renal impairment
  • Rapid renal elimination in normal individuals, hemodialysis for subjects with renal impairment

Reconstitution

  • Instructions for intravenous bolus and intravenous infusion administration
  • Compatibility with various infusion fluids
  • Freshly reconstituted solution is recommended for potency

Storage Conditions

  • Vial should be stored in a cool, dry place (below 30°C), away from light & moisture
  • Keep out of reach of children

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