Merotrax 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Ibn sina pharmaceuticals ltd
Also available as
Merotrax 500 mg injection

Indications

  • Pneumonia
  • Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Bactericidal action by interfering with bacterial cell wall synthesis, potent activity against a broad spectrum of Gram-positive and Gram-negative, aerobic and anaerobic bacteria.

Dosage

  • Adults:
    • Usual dose 500 mg to 1 gm by intravenous administration every 8 hours
    • Dosage varies based on specific infections
  • Children:
    • Dosage ranging from 10 to 40 mg/kg intravenously every 8 hours
    • Specific dosages for different types of infections and patient conditions

Administration

Should be administered by intravenous infusion over approximately 15-30 minutes or as intravenous bolus

Interaction

Competes with Probenecid for active tubular secretion, may reduce serum valproic acid levels

Contraindications

Hypersensitivity to this product

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, and urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B, caution during nursing

Precautions & Warnings

  • Allergic reaction warrants discontinuation
  • Monitoring of liver function in hepatic disease patients

Use in Special Populations

  • Renal Impairment: Dosage reduction required for patients with creatinine clearance less than 51 ml/min
  • Hepatic Impairment: No dosage adjustments necessary, use with caution in dialysis patients
  • Elderly: No dosage adjustments necessary unless creatinine clearance is <51 ml/min
  • Children: Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Symptomatic treatment, haemodialysis for subjects with renal impairment if required

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Intravenous solutions preparation, compatibility with various infusion fluids, potency maintenance

Storage Conditions

Store vial below 30°C, away from light and moisture

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