Merocon 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 750.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Beacon pharmaceuticals plc
Also available as
Merocon 1 gm injection

Indications

  • Treats pneumonia and nosocomial pneumonia
  • Treats urinary tract infections
  • Treats intra-abdominal infections
  • Treats gynaecological infections
  • Treats skin and skin structure infections
  • Treats meningitis
  • Treats septicaemia
  • Treats pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Exerts bactericidal action
  • Interferes with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria
  • Penetrates bacterial cell walls
  • High stability to all serine beta-lactamases
  • Marked affinity for the Penicillin Binding Proteins (PBPs)

Dosage

  • Dependent on type and severity of infection
  • Varied dosage for different types of infections
  • Recommended daily dosage for adults
  • Recommended daily dosage for children
  • Intravenous administration every 8 hours for adults
  • Intravenous administration every 8 hours for children

Administration

  • Administered by intravenous infusion over approximately 15-30 minutes
  • Administered as intravenous bolus over approximately 3-5 minutes

Interaction

  • Probenecid competes with Merocon for active tubular secretion
  • Inhibits renal excretion of Merocon
  • May reduce serum valproic acid levels

Contraindications

  • Contraindicated in patients with demonstrated hypersensitivity to the product

Side Effects

  • Inflammation at the site of injection
  • Thrombophlebitis
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • If allergic reaction occurs, discontinue the drug
  • Careful monitoring of transaminase and bilirubin levels in patients with hepatic disease

Use in Special Populations

  • Dosage reduction in patients with renal impairment
  • No dosage adjustments necessary with impairment of liver function
  • Administration after dialysis for hemodialysis patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Accidental overdose could occur, particularly in patients with renal impairment
  • Symptomatic treatment for overdose

Therapeutic Class

  • Belongs to the class of other beta-lactam antibiotics

Reconstitution

  • Preparation of solution for intravenous bolus administration
  • Preparation of solution for intravenous infusion administration
  • Compatibility with various infusion fluids
  • Recommended use of freshly reconstituted solution

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Keep away from light and moisture
  • Keep out of the reach of children

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