Merocon 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,325.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Beacon pharmaceuticals plc
Also available as
Merocon 500 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

Carbapenem antibiotic for parenteral use, interferes with bacterial cell wall synthesis, potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Dosage and duration depend on type and severity of infection, Recommended daily dosage for adults: 500 mg to 1 gm every 8 hours, for children: 10 to 40 mg/kg intravenously every 8 hours

Administration

Administered by intravenous Infusion over approximately 15-30 minutes or as intravenous bolus over approximately 3-5 minutes

Interaction

Probenecid competes with Merocon for active tubular secretion, Merocon may reduce serum valproic acid levels

Contraindications

Contraindicated in patients with demonstrated hypersensitivity

Side Effects

  • Inflammation
  • Thrombophlebitis
  • Pain at the site of injection
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

Pregnancy Category B, Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Allergic reaction should prompt discontinuation
  • Use with careful monitoring in patients with hepatic disease

Use in Special Populations

  • Renal impairment: Dosage should be reduced in patients with creatinine clearance less than 51 ml/min.
  • Hepatic impairment: No dosage adjustments are necessary
  • Elderly: No dosage adjustments are necessary
  • Use in Children: Efficacy and tolerability in infants under 3 months not established

Overdose Effects

Accidental overdose could occur, treatment should be symptomatic, haemodialysis may be necessary in subjects with renal impairment

Therapeutic Class

Other beta-lactam Antibiotics

Reconstitution

Intravenous bolus Administration and Intravenous infusion administration details provided

Storage Conditions

Store in a cool, dry place below 30°C, away from light and moisture

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