Rosebac 1 gm/vial (IV Injection or Infusion)

1 gm vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Concord pharmaceuticals ltd
Also available as
Rosebac 500 mg injection

Indications

  • Pneumonia and Nosocomial Pneumonia
  • Urinary Tract Infections
  • Intra-abdominal Infections
  • Gynaecological Infections
  • Skin and Skin Structure Infections
  • Meningitis
  • Septicaemia
  • Pulmonary Infections in Cystic Fibrosis
  • Empiric Treatment for Presumed Infections in Patients with Febrile Neutropenia

Pharmacology

  • Bactericidal Action
  • Interference with Bacterial Cell Wall Synthesis
  • Potent Bactericidal Activity Against a Broad Spectrum of Bacteria
  • High Stability to All Serine Beta-lactamases
  • Marked Affinity for Penicillin Binding Proteins

Dosage

  • Recommended Daily Dosage for Adults
  • Recommended Daily Dosage for Children
  • Intravenous Administration
  • Intravenous Infusion
  • Intravenous Bolus
  • Different Dosage for Pneumonia, Urinary Tract Infections, Gynaecological Infections, Nosocomial Pneumonias, Peritonitis, Intra-abdominal Infections, Cystic Fibrosis, and Meningitis

Administration

  • Intravenous Infusion over Approximately 15-30 Minutes
  • Intravenous Bolus over Approximately 3-5 Minutes

Interaction

  • Interaction with Probenecid
  • Effect on Renal Excretion
  • Effect on Serum Valproic Acid Levels

Contraindications

  • Hypersensitivity

Side Effects

  • Inflammation at the Site of Injection
  • Thrombophlebitis
  • Pain at the Site of Injection
  • Skin Reactions like Rash, Pruritus, Urticaria
  • Abdominal Pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • No Adequate and Well-controlled Studies in Pregnant Women
  • Caution during Nursing

Precautions & Warnings

  • Allergic Reaction Management
  • Monitoring of Transaminase and Bilirubin Levels in Patients with Hepatic Disease

Use in Special Populations

  • Dosage Adjustment in Renal Impairment
  • Hemodialysis for Hemodialysis Patients
  • No Dosage Adjustments in Elderly Patients
  • No Experience in Children with Hepatic or Renal Impairment

Overdose Effects

  • Accidental Overdose Risk
  • Symptomatic Treatment
  • Rapid Renal Elimination in Normal Individuals
  • Hemodialysis for Subjects with Renal Impairment

Therapeutic Class

  • Beta-lactam Antibiotics

Reconstitution

  • Preparation of Solution for Intravenous Bolus Administration
  • Preparation of Solution for Intravenous Infusion Administration
  • Compatibility with Various Infusion Fluids
  • Stability of Reconstituted Solution

Storage Conditions

  • Storage Temperature (below 30℃)
  • Protection from Light & Moisture
  • Keep out of the Reach of Children

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