Veronem 500 mg/vial (IV Injection or Infusion)

500 mg vial: ৳ 651.95

Medicine Details

Category Details
Generic Meropenem trihydrate
Company Veritas pharmaceuticals ltd
Also available as
Veronem 1 gm injection

Indications

  • Treatment of pneumonia and nosocomial pneumonia
  • Treatment of urinary tract infections
  • Treatment of intra-abdominal infections
  • Treatment of gynecological infections
  • Treatment of skin and skin structure infections
  • Treatment of meningitis
  • Treatment of septicaemia
  • Treatment of pulmonary infections in cystic fibrosis
  • Empiric treatment for presumed infections in patients with febrile neutropenia

Pharmacology

  • Exerts bactericidal action
  • Interferes with bacterial cell wall synthesis
  • Potent bactericidal activity against a broad spectrum of bacteria

Dosage

  • Recommended dosage for adults
  • Recommended dosage for children
  • Intravenous administration every 8 hours

Administration

  • Administered by intravenous infusion
  • Administered over approximately 15-30 minutes
  • Administered as an intravenous bolus over approximately 3-5 minutes

Interaction

  • Interaction with probenecid
  • Competes for active tubular secretion
  • May reduce serum valproic acid levels

Contraindications

  • Contraindicated in patients with demonstrated hypersensitivity

Side Effects

  • Inflammation at injection site
  • Thrombophlebitis
  • Pain at injection site
  • Skin reactions like rash, pruritus, urticaria
  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution advised during nursing

Precautions & Warnings

  • Caution in patients with hepatic disease
  • Monitoring of transaminase and bilirubin levels

Use in Special Populations

  • Dosage adjustment in renal impairment
  • No dosage adjustments in hepatic impairment
  • Monitoring required for elderly patients
  • Efficacy and tolerability in infants under 3 months not established

Overdose Effects

  • Accidental overdose may occur
  • Symptomatic treatment advised
  • Rapid renal elimination in normal individuals
  • Haemodialysis may be necessary in subjects with renal impairment

Therapeutic Class

  • Belongs to the class of other beta-lactam antibiotics

Reconstitution

  • Preparation of solution for intravenous bolus administration
  • Preparation of solution for intravenous infusion administration
  • Compatibility with various infusion fluids
  • Freshly reconstituted solution recommended
  • Maintains potency for up to 3 hours at up to 25°C or 13 hours at up to 5°C

Storage Conditions

  • Store in a cool, dry place below 30°C
  • Protection from light and moisture
  • Keep out of the reach of children

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