Combicard 5 mg+50 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)

Strip Price: ৳ 70.00

Medicine Details

Category	Details
Generic	Amlodipine besilate atenolol
Company	Healthcare pharmaceuticals ltd

Indications

Essential hypertension
Angina pectoris
Post Ml patients
Refractory angina pectoris

Pharmacology

Dihydropyridine calcium antagonist
Peripheral vasodilator
Cardioselective beta-blocker
Reduction in peripheral vascular resistance and blood pressure
Reduction in myocardial oxygen demand
Negative inotropic and negative chronotropic effects

Dosage & Administration

Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
Dosage may be increased to 5/25 mg two tablets daily or as advised by physicians
Dosage should be individualized

Interaction

Disopyramide: Reduced clearance and additive negative inotropic effects
Ampicillin: Potential reduction in Atenolol levels
Oral antidiabetics and insulin: Tissue sensitivity and insulin secretion inhibition

Contraindications

Hypersensitivity to either component
Sinus bradycardia
Higher degrees of heart block
Cardiogenic shock
Hypotension
Congestive heart failure
Poor left ventricular function

Side Effects

Fatigue
Headache
Edema
Nausea
Drowsiness
Anxiety
Depression

Pregnancy & Lactation

Use during pregnancy if expected benefit outweighs potential fetal risk
Not recommended for nursing mothers
Breastfeeding cessation if necessary

Precautions & Warnings

Caution in patients with airway obstruction
Use in renal impairment with caution
Caution in severe liver damage
Gradual drug withdrawal advised

Overdose Effects

Hypotension
Congestive cardiac failure
Unabsorbed drugs removal by gastric lavage or activated charcoal administration
Symptomatic treatment suggested

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Keep below 30°C, away from light and moisture, out of reach of children

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