Tetracycline 500 mg (Capsule)
Unit Price: ৳ 2.29 (100's pack: ৳ 228.76)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tetracycline hydrochloride oral |
| Company | Reliance pharmaceuticals ltd |
Indications
- Ricketsial infection
- Mycoplasma pneumoniae infections in adults
- Chlamydial Infections
- Non-gonococcal or non specific urethritis
- Lyme disease
- Brucellosis
- Granuloma inguinale
- Cholera
- Glanders
- Relapsing fever
- V. vulnifians
- Urinary Tract Infections
- Bronchitis
- Pelvic inflammatory disease
- Travelers diarrhea
- Acne vulgaris
- Prostatitis
- Anaerobic infections
Pharmacology
- Mechanism of action on protein synthesis
- Active transport system
- Bacterial cell penetration
- Specific binding to 30s ribosomes
- Inhibition of bacterial protein synthesis
- Susceptibility to Gram positive aerobic Cocci
- Resistance in staphylococci and streptococci
- Activity against Pseudomonas and Enterobacteriaceae
- Incompletely absorbed from the gastrointestinal tract
- Wide distribution in body tissues and fluids
- Excretion in urine and feces
Dosage & Administration
- Usual adult oral dosage
- Usual oral dosage for children
- Preferable intake timing in relation to meals
- Specific dosage for Acne vulgaris
- Specific dosage for acute staphylococcal infections
- Specific dosage for acute streptococcal infections
- Specific dosage for Amoebiasis
- Specific dosage for Brucellosis
- Specific dosage for subacute bacterial endocarditis
- Specific dosage for Syphilis
Interaction
- Impaired absorption with antacids containing divalent and trivalent cations
- Interference with the bactericidal action of penicillin
- Potentiation of the effect of anticoagulants
- Decreased efficacy of oral contraceptives
- Possible exacerbation of nephrotoxic effects
- Potential increase in hypoglycemic effect
- Possible increase in toxic effects of ergot alkaloids and methotrexate
Contraindications
- Hypersensitivity to any tetracycline member
- Cross-sensitivity in tetracycline groups
- Avoidance in patients with systemic lupus erythematosus
- Consideration of avoidance in severe renal impairment
Side Effects
- Depression of bone growth
- Teeth discoloration during tooth development
- Enamel hypoplasia
- Hypersensitivity reactions
- Photosensitivity reactions
- Gastrointestinal effects
- Epigastric distress
- Nausea
- Dose-related vomiting
- Accentuated prerenal azotemia
- Superinfections with oral and anogenital candidiasis
- Esophageal ulcerations
Pregnancy & Lactation
- Risk of hypertoxicity in mother
- Effects on developing fetus
- Impaired bone growth in children
- Permanent discoloration of child's teeth
Precautions & Warnings
- Caution in patients with impaired liver function
- Avoidance of high doses
- Avoidance of concomitant administration with potential hepatotoxic drugs
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store between 20-25C