Tetracycline 250 mg (Capsule)
Unit Price: ৳ 1.32 (100's pack: ৳ 132.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tetracycline hydrochloride oral |
| Company | Pharmadesh laboratories ltd |
Indications
- Ricketsial infection
- Mycoplasma pneumoniae infections
- Chlamydial Infections
- Lyme disease
- Brucellosis
- Urinary Tract Infections
- Bronchitis
- Pelvic inflammatory disease
- Travelers diarrhoea
- Acne vulgaris
- Prostatitis
- Anaerobic infections
Pharmacology
- Main mechanism of action on protein synthesis
- Energy-dependent active transport system
- Binds to the 30s ribosomes
- Inhibit bacterial protein synthesis
- Susceptibility to various bacteria
- Urinary concentrations for E. coli
- Active against anaerobic species of bacteria
- High concentrations in the gastrointestinal contents
- Half-life of about 12 hours
- Excreted in the urine and in the faeces
Dosage & Administration
- Usual adult oral dosage of 1-2g daily
- Usual oral dosage for children
- Dosage for specific indications like Acne vulgaris, staphylococcal infections, streptococcal infections, amoebiasis, brucellosis, subacute bacterial endocarditis, syphilis
Interaction
- Impaired absorption with antacids containing certain cations
- Interference with the bactericidal action of penicillin
- Potentiation of the effect of anticoagulants
- Decrease efficacy of oral contraceptives
- Potential increase in hypoglycaemic effect of insulin and sulfonylureas
- Potential increase in toxic effects of ergot alkaloids and methotrexate
Contraindications
- Hypersensitivity to tetracycline groups
- Cross-sensitivity with other tetracycline members
- Systemic lupus erythematosus
- Renal impairment
Side Effects
- Teeth and bone-related effects
- Hypersensitivity reactions
- Photosensitivity reactions
- Gastrointestinal effects
- Accentuated prerenal azotemia
- Superinfections with oral and anogenital candidiasis
- Esophageal ulcerations
Pregnancy & Lactation
- Not to be used during pregnancy
- Potential effects on the developing fetus
- Risk of impaired bone growth and teeth discoloration in children
Precautions & Warnings
- Caution in patients with impaired liver function
- Avoid high doses in patients with impaired liver function
- Avoid concomitant use with potential hepatotoxic drugs
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store between 20-25°C