Tetrax 500 mg (Capsule)
Unit Price: ৳ 3.39 (10 x 10: ৳ 339.00)
Strip Price: ৳ 33.90
Medicine Details
| Category | Details |
|---|---|
| Generic | Tetracycline hydrochloride oral |
| Company | Square pharmaceuticals plc |
Indications
- Rocky Mountain spotted fever treatment
- Mycoplasma pneumoniae infections treatment
- Chlamydial infections treatment
- Lyme disease treatment
- Brucellosis treatment
- Urinary tract infections treatment
- Pelvic inflammatory disease treatment
- Acne vulgaris treatment
- Prostatitis treatment
- Syphilis alternative treatment
- Anaerobic infections treatment
- Traveler's diarrhea treatment
Pharmacology
- Inhibition of bacterial protein synthesis
- Susceptibility to Gram positive aerobic Cocci
- Resistance in staphylococci, streptococci, and some pneumococci
- Resistance in Pseudomonas and many Enterobacteriaceae
- Activity against Brucella species
- Activity against Vibrio cholerae and V. vulnificus
- Activity against anaerobic species of bacteria
- Absorption from the gastrointestinal tract
- Distribution in body tissues and fluids
- Half-life of approximately 12 hours
- Excretion in urine and feces
Dosage & Administration
- Usual adult oral dosage of 1-2g daily
- Usual oral dosage for children older than 8 years in 25-50mg/kg daily
- Preferable intake one hour before or 2 hours after meals
- Specific dosage for Acne vulgaris, staphylococcal infections, streptococcal infections, amoebiasis, brucellosis, subacute bacterial endocarditis, syphilis
Interactions
- Impaired absorption with antacids containing divalent and trivalent cations
- Interference with bactericidal action of penicillin
- Potentiation of anticoagulant effects
- Decreased efficacy of oral contraceptives
- Potential exacerbation of nephrotoxic effects by diuretics or other nephrotoxic drugs
- Potential increase in hypoglycemic effect of insulin and sulfonylureas in patients with DM
- Increased toxic effects of ergot alkaloids and methotrexate
Contraindications
- Hypersensitivity to tetracycline
- Systemic lupus erythematosus
- Renal impairment
Side Effects
- Depression of bone growth
- Graybrown discoloration of teeth
- Enamel hypoplasia
- Hypersensitivity reactions
- Photosensitivity reactions
- Gastrointestinal effects
- Accentuated prerenal azotemia
- Superinfections with oral and anogenital candidiasis
- Esophageal ulcerations
Pregnancy & Lactation
- Avoidance during pregnancy and lactation
- Risk of hypertoxicity in the mother and effects on the developing fetus
- Potential impairments in bone growth and discoloration of child's teeth
Precautions & Warnings
- Caution in patients with impaired liver function
- Avoidance of high doses
- Avoidance of concomitant administration with potentially hepatotoxic drugs
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Store between 20-25°C