Doxacin 100 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Desh pharmaceuticals ltd |
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Description
Highly active broad-spectrum antibiotic of tetracycline group effective against a wide range of bacteria, spirochete, mycoplasma, rickettsia and mycobacteria.
Mode of Action
Bacteriostatic antibiotic with spectrum of activity against Staphylococcus aureus, Nocardia, E. coli, Proteus mirabilis, Klebsiella, Haemophilus influenzae, Chlamydia, Mycoplasma, Rickettsiae, spirochetes, Plasmodium falciparum, and more.
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Interaction
Absorption impaired by antacids, iron-containing preparations, and bismuth salicylate. Decreased half-life with barbiturates, carbamazepine, and phenytoin. Render oral contraceptive less effective. May require anticoagulant dosage adjustment. Avoid giving tetracyclines with penicillin.
Contraindications
Hypersensitivity, children under 8 years, pregnant women, and lactating mothers.
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
Avoid in pregnant women and breastfeeding mothers due to risk of staining and effect on bone growth in the fetus, and entry into breast milk.
Precautions & Warnings
Avoid during tooth development to prevent permanent discoloration of teeth.
Therapeutic Class
Tetracycline group of drugs
Storage Conditions
Keep in cool, dry place protected from light.