Doxizen 100 mg (Capsule)
Unit Price: ৳ 2.15 (10 x 10: ৳ 215.00)
Strip Price: ৳ 21.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Zenith pharmaceuticals ltd |
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Description
- Highly active broad-spectrum antibiotic
- Effective against Gram-positive and Gram-negative bacteria
- Effective against spirochete, mycoplasma, rickettsia, and mycobacteria
- Used as an alternate to penicillin in the treatment of gonorrhea and syphilis
- Main mechanism of action on protein synthesis
Pharmacology
- Semisynthetic tetracycline antibiotic
- Bacteriostatic antibiotic
- More active against Staphylococcus aureus and Nocardia
- Active against penicillin-resistant strains of Staphylococcus aureus
- Sensitive to certain Gram-negative strains of E. coli, Proteus mirabilis, and Klebsiella
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia: 100 mg twice daily for 7-21 days
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Impaired absorption by antacids containing aluminum, calcium, or magnesium, and iron-containing preparations
- Impaired absorption by bismuth salicylate
- Barbiturates, carbamazepine, and phenytoin decrease half-life
- Concurrent use may render oral contraceptives less effective
- Anticoagulant therapy may require downward adjustment of dosages
- Avoid giving in conjunction with penicillin
Contraindications
- Hypersensitivity to any of the tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anemia
- Eosinophilia
Pregnancy & Lactation
Avoid in pregnant women and breastfeeding mothers
Precautions & Warnings
Avoid use during tooth development in children under 8 years of age
Therapeutic Class
Tetracycline group of drugs
Storage Conditions
Store in a cool and dry place, protected from light