Fardox 100 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Pharmadesh laboratories ltd |
Indications
- Respiratory tract infections: Pneumonia, influenza, sinusitis, bronchitis, tonsillitis, tracheitis
- Gastrointestinal tract infections: Cholera, traveler's diarrhea, shigella dysentery, acute intestinal amebiasis
- Chlamydial infections: Lympho-granuloma venereum, psittacosis, trachoma
- Sexually transmitted diseases: Non-gonococcal urethritis, acute pelvic inflammatory disease, uncomplicated urethral and endocervical or rectal infections, gonorrhea, syphilis, pyelonephritis, cystitis
- Other infections: Impetigo, furunculosis, inclusion conjunctivitis, brucellosis, tularemia, cellulitis, acne, Q-fever
Description
Fardox is a highly active broad-spectrum antibiotic of tetracycline group effective against a wide range of bacteria, spirochete, mycoplasma, rickettsia, and mycobacteria, with its main mechanism of action on protein synthesis.
Pharmacology
Doxycycline Hydrochloride is a semisynthetic tetracycline antibiotic with broad spectrum activity, primarily a bacteriostatic antibiotic, and active against various bacteria, including penicillin-resistant strains of Staphylococcus aureus.
Dosage
Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days. Severe infections: 200 mg daily for 10 days. Acne: 100 mg daily. Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Interaction
Absorption of tetracyclines is impaired by antacids containing aluminium, calcium or magnesium, iron-containing preparations, and bismuth salicylate. Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline. Concurrent use of tetracyclines may render oral contraceptives less effective.
Contraindications
Doxycycline is contraindicated in patients with hypersensitivity to any tetracyclines, children under 8 years of age, pregnant women, and lactating mothers.
Side Effects
Nausea, vomiting, diarrhea, skin rashes, hemolytic anemia, eosinophilia may be reported as side effects.
Pregnancy & Lactation
Doxycycline should be avoided in pregnant women due to the risk of staining and effect on bone growth in the fetus. It enters breast milk, so mothers taking these drugs should not breastfeed.
Precautions & Warnings
The use of tetracyclines during tooth development may cause permanent discoloration of teeth, so should not be used in the last half of pregnancy, infancy, childhood up to 8 years.
Therapeutic Class
Tetracycline group of drugs
Storage Conditions
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light