Imped Plus 5 mg+25 mg (Tablet)
Unit Price: ৳ 4.00 (100's pack: ৳ 400.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Rephco pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris and hypertension as co-existing diseases
- Post myocardial infarction
- Refractory angina pectoris
Pharmacology
- Fixed-dose combination of Amlodipine and Atenolol
- Dihydropyridine calcium antagonist
- Peripheral vasodilator
- Cardioselective beta-blocker
- Reduction in peripheral vascular resistance
- Reduction in blood pressure
- Decrease in coronary vasoreactivity
- Lowering of cardiac demand
- Reduction in myocardial oxygen demand
Dosage & Administration
- Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily
- Dosage should be individualized
Interaction
- Disopyramide: Atenolol reduces the clearance of disopyramide by 20%
- Ampicillin: May reduce Atenolol levels at doses of 1 gm and above
- Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side Effects
- Fatigue
- Headache
- Edema
- Nausea
- Drowsiness
- Anxiety
- Depression
Pregnancy & Lactation
- Should be used during pregnancy only if the expected benefit outweighs the potential fetal risk
- Should not be used by nursing mothers
- If its use is considered necessary, breast-feeding should be stopped
Precautions & Warnings
- Bronchospasm
- Renal impairment
- Hepatic impairment
- Drug withdrawal
Overdose Effects
- Hypotension
- Congestive cardiac failure
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children