Megadox 100 mg (Capsule)
Unit Price: ৳ 2.16 (10 x 10: ৳ 216.00)
Strip Price: ৳ 21.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxycycline hydrochloride |
| Company | Beximco pharmaceuticals ltd |
Title and Categories
- Megadox - Tetracycline Antibiotic
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Impetigo
- Furunculosis
- Inclusion conjunctivitis
- Brucellosis
- Tularemia
- Cellulitis
- Acne
- Q-fever
Antibiotic Group
- Tetracycline
Pharmacology
- Bacteriostatic antibiotic
- Broad spectrum activity
- Active against Gram-positive and Gram-negative bacteria
- Inhibits protein synthesis
Mode of Action
- Inhibition of protein synthesis
- Activity against Staphylococcus aureus and Nocardia
- Resistance against penicillin-resistant strains
- Sensitivity to various anaerobes
- Activity against Haemophilus influenzae and Nocardia
- Activity against Chlamydia, Mycoplasma, and Rickettsiae
- Activity against spirochetes and Plasmodium falciparum
Dosage
- Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days
Administration
- Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing
Interaction
- Impaired absorption by antacids and iron-containing preparations
- Decreased half-life by barbiturates, carbamazepine, and phenytoin
- Rendering oral contraceptives less effective
- Requirement of downward adjustment of anticoagulant dosages
- Avoidance in conjunction with penicillin
Contraindications
- Hypersensitivity to tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Skin rashes
- Hemolytic anaemia
- Eosinophilia
Pregnancy & Lactation
- Avoidance in pregnant women
- Inhibition of breastfeeding by mothers taking the drug
Precautions & Warnings
- Avoidance in the last half of pregnancy, infancy, and childhood to the age of 8 years due to potential tooth discoloration
Therapeutic Class
- Tetracycline group of drugs
Storage Conditions
- Keep out of reach of children
- Store in a cool and dry place, protected from light