Mardox 100 mg (Capsule)
Medicine Details
Category | Details |
---|---|
Generic | Doxycycline hydrochloride |
Company | Marksman pharmaceuticals ltd |
Title
Mardox Broad-Spectrum Antibiotic
Categories
- Medicine
- Antibiotics
- Tetracycline
Description
Highly active broad-spectrum antibiotic of tetracycline group effective against a wide range of bacteria, spirochete, mycoplasma, and mycobacteria.
Indications
- Respiratory tract infections
- Gastrointestinal tract infections
- Chlamydial infections
- Sexually transmitted diseases
- Other infections
Pharmacology
Semisynthetic tetracycline antibiotic with broad-spectrum activity primarily bacteriostatic and effective against Staphylococcus aureus, Nocardia, E. coli, Proteus mirabilis, Klebsiella, Haemophilus influenzae, Chlamydia, Mycoplasma, Rickettsiae, spirochetes, and Plasmodium falciparum.
Dosage
- 200 mg on first day, then 100 mg daily for 7-10 days
- Severe infections: 200 mg daily for 10 days
- Acne: 100 mg daily
- Uncomplicated genital chlamydia: 100 mg twice daily for 7-21 days
Administration
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Interaction
- Impaired absorption by antacids, iron preparations, and bismuth salicylate
- Decreased half-life with barbiturates, carbamazepine, and phenytoin
- Rendering oral contraceptives less effective
- Downward adjustment of anticoagulant dosages
- Avoid concurrent use with penicillin
Contraindications
- Hypersensitivity to tetracyclines
- Children under 8 years of age
- Pregnant women
- Lactating mothers
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Skin rashes
- Hemolytic anemia
- Eosinophilia
Pregnancy & Lactation
Avoided in pregnant women and nursing mothers due to staining and effects on bone growth in the fetus and entry into breast milk
Precautions & Warnings
Avoid use during tooth development in children under 8 years to prevent permanent tooth discoloration
Therapeutic Class
Tetracycline group of drugs
Storage Conditions
Keep in a cool, dry place protected from light